Cell fate engineering ------------------------ - Terminology: + Direct programming + Directed differentiation + Reprogramming + Direct conversion - How TF pools are defined and refined - Computational means to define factor cocktails + Expression alone (D'Alessio et al) + Expression + GRN (Cahan et al 2014; Rackham et al 2016; Hartmann 2018) - Comparison of directed differentiation and direct programming with scRNAseq (Briggs et al 2017) ----