Trajectory inference

• Background

• when to use it

• what to use it for

• How is it done?

• dimensionality reduction

• trajectory modeling

• Monocle paper

• Myoblast differentiation

• overview of method

• Minimal spanning tree

• graph diameter

• myofibroblasts

• robustness

• expression programs

• regulators via motif enrichment

• functional testing

• Slingshot

• Dyngen

• HW 2

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