ATACseq

• DNA packaging

• Various types of enzymes that cut DNA

• DNase I hypersensitive sites (DHSs)

• DNase profiling

• ENCODE

• DHS and ChIP-Seq

• Mapping enhancer-to-promoter

• Limitations of DNase-Seq & friends

• Tn5 Transposase & ATAC-seq

• Size distribution distinguishes nucleosome free from spanning

• Transcription start sites (TSS)

• TF fottprinting

• scATAC-seq

• scATAC-seq of HSPCs

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